Heart 2009;95:1038-1040
Editorials
Lesions without calcium: lessons from CT angiography
Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
Dr Joanne Schuijf, Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands; j.d.schuijf@lumc.nl
| The first 150 words of the full text of this article appear below. |
Within the management of patients with known or suspected coronary artery disease (CAD), non-invasive coronary atherosclerosis imaging techniques are gradually gaining their position in addition to the more traditional functional imaging techniques. Coronary artery calcium scoring (CACS) in particular has been studied for almost two decades, initially by means of electron beam computed tomography (EBCT), while more recently multidetector row computed tomography (MDCT) is being used. Although CACS was heavily disputed at first, a wealth of data are currently available supporting its value as a non-invasive marker for atherosclerosis. Both prospective studies and retrospective systematic meta-analyses have demonstrated that the likelihood of cardiovascular events is strongly related to the extent of coronary calcium. Recent long-term observations from a large registry of 25 253 patients confirmed that 10-year survival (after adjustment for risk factors, including age) decreased from 99.4% in the absence of calcium to 87.8% for a CACS exceeding 1000 (p<0.0001).1
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Heart 2009 95: 1056-1060.[Abstract] [Full Text] [PDF]
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