JournalScan
| The first 150 words of the full text of this article appear below. |
GENERAL CARDIOLOGY
Renal sympathetic efferent and afferent nerves are crucial for the initiation and maintenance of systemic hypertension, and as such renal sympathetic denervation is a potential therapeutic target for hypertension. Krum et al describe the development of a novel, percutaneous, catheter-based approach to renal sympathetic denervation. The lumen of the main renal artery is cannulated and the surrounding sympathetic nerves destroyed by radiofrequency waves, and in a swine model this technique has been show to reduce noradrenaline content in the kidney by as much as 85%.
Fifty patients received percutaneous radiofrequency catheter-based treatment between June 2007 and November 2008, with subsequent follow-up to 1 year. The primary end points were office blood pressure and safety data at 1, 3, 6, 9 and 12 months after the procedure. Both renal and magnetic resonance angiography were performed to ensure no anatomical damage from the procedure, and the effectiveness of blood pressure lowering was
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
- Full Text
- Full Text (PDF)
- Submit a response
- Alert me when this article is cited
- Alert me when eLetters are posted
- Alert me if a correction is posted
Services
- Email this link to a friend
- Similar articles in this journal
- Add article to my folders
- Download to citation manager
- Request Permissions
Google Scholar
PubMed
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
