Education in Heart
Triple antithrombotic management after stent implantation: when and how?
Deutsches Herzzentrum München and 1. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, Germany
Correspondence to:
Professor Albert Schömig, Deutsches Herzzentrum München, Lazarettstr. 36, 80636 Munich, Germany; aschoemig@dhm.mhn.de
| The first 150 words of the full text of this article appear below. |
Inhibition of platelet activation is a cornerstone of adjunctive medical treatment during and after percutaneous coronary interventions with stent implantation (PCI-S) in order to prevent acute and long term thrombotic complications. Dual antiplatelet therapy (DAT) with aspirin and clopidogrel has been proven to be very effective at preventing adverse events such as acute and subacute stent thrombosis, myocardial infarction, and death after coronary stenting, for both bare metal stents (BMS) and drug eluting stents (DES). Oral anticoagulation (OAC) is the recommended treatment for patients at risk of thromboembolic events due to atrial fibrillation, mechanical heart valves, deep vein thrombosis, pulmonary embolism and left ventricular thrombi. The number of patients who have an indication for both DAT and OAC is increasing, since more patients who are already on OAC are scheduled for percutaneous coronary interventions and some patients who are on DAT will develop a medical condition which requires OAC. Consequently,
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