Education in Heart
Virtual histology and optical coherence tomography: from research to a broad clinical application
Thoraxcenter, Erasmus MC, Rotterdam, The Netherlands
Correspondence to:
Dr Hector M Garcia-Garcia, Thoraxcenter – Erasmus MC, z120 Dr Molerwaterplein 40, 3015 GD Rotterdam, The Netherlands; h.garciagarcia@erasmusmc.nl
| The first 150 words of the full text of this article appear below. |
Invasive coronary imaging techniques have improved our understanding of atherosclerosis and helped us to evaluate the effectiveness of new drugs and new intravascular devices. We have adopted and integrated them rapidly into our clinical decision making process in the catheterisation laboratory. So far, only significant lesions in the coronary angiogram have been treated either by percutaneous coronary intervention (PCI) or coronary bypass artery grafting (CABG), while normal looking coronary segments in angiography have been regarded as "disease-free", and mild/moderate stenoses as "non-treatable" by PCI or CABG; from these non-significantly diseased areas, acute coronary events may potentially arise. In response to this, many imaging coronary techniques have been developed to study these areas in order to understand better the pathophysiology of atherosclerotic disease and to assess the performance of medical interventions that may ultimately have an important impact on the prevention of acute myocardial infarction and death.
Grey scale intravascular ultrasound
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