Heart 2009;95:1725-1726
Editorial
What causes outflow tract obstruction in hypertrophic cardiomyopathy?
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, USA
Correspondence to Professor S R Ommen, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA; ommen.steve@mayo.edu
| The first 150 words of the full text of this article appear below. |
The first descriptions of patients impacted with what has become known as hypertrophic cardiomyopathy occurred roughly 50 years ago.1 2 Careful examination involving both auscultatory and palpatory physical findings and, subsequently, invasive haemodynamics led to the appreciation of dynamic subvalvular obstruction. Thus began an era of intense haemodynamic assessment into this fascinating condition which has come to be appreciated in most cases as a disease of not only left ventricular hypertrophy but also dynamic impedance to left ventricular ejection. There has also been a considerable degree of controversy over the existence of, mechanisms of, and treatments for this unique type of haemodynamic abnormality.
There had been considerable debate, prominently featured at the annual sessions of the American Heart Association several decades ago, on whether there is true obstruction as opposed to systolic cavity obliteration.3 4 5 6 Today, we recognise that both situations can exist, but there are clearly many patients who have true
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Heart 2009 95: 1784-1791.[Abstract] [Full Text] [PDF]
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