Heart 2009;95:439-440
Editorials
States, rates and traits: prognosis research and chronic stable angina
Dr Harry Hemingway, Department of Epidemiology and Public Health, UCL Medical School, 1–19 Torrington Place, London WC1E 6BT, UK; h.hemingway@ucl.ac.uk
| The first 150 words of the full text of this article appear below. |
From what state are patients suffering now, and how will this change in the future? What events might punctuate this suffering, and at what rate will they accrue? What biological, behavioural and psychosocial traits lead people to these different states? These fundamental questions of prognosis research are as obvious as they are incompletely addressed. Enquiry into the future progression of people with existing disease is, or should be, a cornerstone of clinical practice, and translational medicine, and while we do know much about death after myocardial infarction, we know much less about prognosis in relation to other startpoints and other endpoints.
To illustrate the slow progress in understanding the prognosis of stable angina, imagine that this editorial were written by Warren and Bracket, who in 1812 wrote the first article in the first edition of the New England Journal of Medicine and Surgery,1 entitled "Remarks on angina pectoris." One
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