Reverse Remodeling in Heart Failure with Cardiac Resynchronization Therapy

Martin G St John Sutton ^1*

¹ University of Pennsylvania, United States

^* To whom correspondence should be addressed. E-mail: suttonm{at}mail.med.upenn.edu.

Accepted 26 March 2006

Abstract

Prevalence of heart failure Congestive heart failure (CHF) is a major health problem involving almost 22 million subjects worldwide. Heart failure is also the most common hospital discharge diagnosis in patients over sixty-five years of age (1). Approximately two thirds of patients presenting with symptoms of CHF have impaired systolic function with left ventricular ejection fraction (LVEF<50%), and one third have diastolic dysfunction of varying severity but preserved systolic function (LVEF>50%) (2). This current perspective is confined to patients with chronic severe systolic heart failure.

Keywords: cardiac resynchronization, heart failure, quantitative doppler echocardiography

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