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The most recent version of this article was published on 1 February 2007

Heart. Published Online First: 27 April 2006. doi:10.1136/hrt.2005.067967
Copyright © 2006 BMJ Publishing Group Ltd & British Cardiovascular Society

Reviews

Reverse Remodeling in Heart Failure with Cardiac Resynchronization Therapy

Martin G St John Sutton 1* and Martin Keane 1

1 University of Pennsylvania, United States

* To whom correspondence should be addressed. E-mail: suttonm{at}mail.med.upenn.edu.

Accepted 26 March 2006


Abstract

Prevalence of heart failure Congestive heart failure (CHF) is a major health problem involving almost 22 million subjects worldwide. Heart failure is also the most common hospital discharge diagnosis in patients over sixty-five years of age (1). Approximately two thirds of patients presenting with symptoms of CHF have impaired systolic function with left ventricular ejection fraction (LVEF<50%), and one third have diastolic dysfunction of varying severity but preserved systolic function (LVEF>50%) (2). This current perspective is confined to patients with chronic severe systolic heart failure.

Keywords: cardiac resynchronization, heart failure, quantitative doppler echocardiography


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  • Zhang, Q, Fung, J W-H, Chan, J Y-S, Yip, G, Lam, Y-Y, Liang, Y-J, Yu, C-M (2009). Difference in long-term clinical outcome after cardiac resynchronisation therapy between ischaemic and non-ischaemic aetiologies of heart failure. Heart 95: 113-118 [Abstract] [Full Text]  

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