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The most recent version of this article was published on 1 August 2006

Heart. Published Online First: 12 May 2006. doi:10.1136/hrt.2005.083840
Copyright © 2006 BMJ Publishing Group Ltd & British Cardiovascular Society

Editorials

The effect of diabetes on the fetal heart

Lisa K Hornberger 1*

1 UCSF, United States

* To whom correspondence should be addressed. E-mail: lisa.hornberger{at}ucsf.edu.

Accepted 14 April 2006


Abstract

Maternal diabetes mellitus significantly affects the fetal heart and fetal-placental circulation in both structure and function. The influence of pre-conceptional diabetes begins during embryonic development in the first trimester, with altered cardiac morphogenesis and placental development. It continues to have an influence on the fetal circulation through the second and third trimesters and into the perinatal and neonatal period.

Keywords: congenital heart disease, diabetes mellitus, fetal echocardiography, hypertrophic cardiomyopathy


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