In this issue of Heart, Drs Sekikawa and colleages (See page 569) report a population based cohort study comparing coronary calcium scores and serum concentrations of long chain n-3 polyunsaturated fatty acids (n-3 PUFA) in Japanese and white men. Interestingly, not only did Japanese men have much higher serum levels of n-3 PUFA but they also had a lower rate of coronary calcification. Multivariate analysis considering standard risk factors supported an association between serum n-3 PUFA levels and coronary calcification (see table 1).