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Basic mechanisms for adverse cardiovascular events associated with air pollution
  1. Michael T Chin
  1. Division of Cardiology, Department of Medicine, University of Washington, Seattle, Washington, USA
  1. Correspondence to Dr Michael T Chin, Center for Cardiovascular Biology, UW Medicine at South Lake Union, Box 358050, 850 Republican Street, Brotman 353, Seattle, WA 98109, USA; mtchin{at}u.washington.edu

Abstract

Air pollution is a significant cause of cardiovascular morbidity and mortality worldwide. Although the epidemiologic association between air pollution exposures and exacerbation of cardiovascular disease (CVD) is well established, the mechanisms by which these exposures promote CVD are incompletely understood. This review provides an overview of the components of air pollution, an overview of the cardiovascular effects of air pollution exposure, and a review of the basic mechanisms that are activated by exposure to promote CVD.

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