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The spectrum of coronary artery disease and risk of myocardial infarction
Clinicians often dichotomize coronary artery disease (CAD) on the basis of obstruction to blood flow given the implications of this threshold on considerations for revascularization. As a result, nonobstructive CAD is often characterized as less significant, although this may oversimplify the risks associated with nonobstructive disease. In this retrospective cohort of patients who underwent elective coronary angiography in the Veterans Affairs health care system, the authors evaluated the relationship between gradations of CAD burden and 1-year outcomes of non-fatal myocardial infarction (MI) and mortality. CAD burden was defined by both thresholds for no CAD, nonobstructive CAD, and obstructive CAD as well as the number of vessels involved (1-vessel, 2-vessel, or 3-vessel/left …
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