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ASSA14-01-06 One-year outcomes in Chinese patients with acute coronary syndromes: a subanalysis of EPICOR Asia study
  1. Y Huo1,
  2. YL Han2,
  3. JB Ge3,
  4. JY Chen4,
  5. ZY Yuan5,
  6. SB Qiao6,
  7. B Yu7
  1. 1Department of Cardiology, Peking University First Hospital, Beijing, China
  2. 2Department of Cardiology, The General Hospital of Shenyang Military Region, Shenyang, China
  3. 3Department of Cardiology, Zhongshan Hospital Affiliated to Fu Dan University, Shanghai, China
  4. 4Department of Cardiology, Guangdong General Hospital, Guangdong, China
  5. 5Department of Cardiology, First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Shanxi, China
  6. 6Department of Cardiology, Fu Wai Hospital, Beijing, China
  7. 7Department of Cardiology, The 2nd Affiliated Hospital of Harbin Medical University, Harbin, China

Abstract

Objectives The outcomes of Chinese patients with acute coronary syndromes (ACS) remain unclear. This study aimed to investigate the 1-year outcomes of Chinese patients with ST segment elevation myocardial infarction (STEMI), non-STEMI (NSTEMI) and unstable angina (UA).

Methods This is a subanalysis of Long-tErm follow-uP of antithrombotic management patterns In Acute CORonary Syndrome patients in Asia (EPICOR Asia) study (NCT01361386), a prospective, multinational, observational study on ACS patients after discharge with 2-year follow-up. One-year follow-up outcomes of Chinese patients with ACS were reported based on the final diagnosis of STEMI, NSTEMI or UA, which were confirmed by an independent validation committee.

Results Eight thousand two hundred and fourteen Chinese patients with ACS were finally included in this study (STEMI, n = 3961; NSTEMI, n = 1315; UA, n = 2938). The baseline characteristics of patients were reported in Table 1. The one-year incidences of cardiovascular/cerebrovascular event (20.5%), congestive heart failure (2.1%), primary ischaemic stroke (1.4%), and death (3.7%) were highest in patients with NSTEMI (overall p < 0.01 vs STEMI) (Table 2). Additionally, the mortality of patients with UA was significantly lower than that of STEMI patients (p < 0.001). The one-year incidence of bleeding event is the same in STEMI and NSTEMI patients. The accumulated mortality in patients with STEMI, NSTEMI and UA all increased with one year follow-up (Figure 1).

Abstract ASSA14-01-06 Table 2 One-year post-discharge outcomes of patients by final diagnosis

Abstract ASSA14-01-06 Figure 1

The accumulated mortality of patients with STEMI, NSTEMI and UA at 1, 3 and 12 months after hospital discharge

Conclusion The outcomes of Chinese patients with NSTEMI were poorer than that of STEMI and UA. Therefore, further studies are needed to identify ideal therapeutic algorithm for these patients in China.

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