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The Authors’ reply
We would like to thank Dr Cunnington for his interest in our study1 and raising some potentially interesting points.2 We do not have a breakdown of patients with heart failure (HF) who had either preserved (HFpEF) or reduced ejection fraction (HFrEF). Since β-blockers only have a licensed indication for HFrEF on the basis of an echocardiogram, we do not believe that this is likely to be a relevant factor within our dataset. The relative prevalence of hypertension within our cohort was 13.3% vs 11.6% and for diabetes was 47.4% vs 41.9%, respectively, for HF alone versus HF with chronic obstructive pulmonary disease (COPD). Hence, the assertion made regarding a higher putative comorbidity is not …
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