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Effect of supplemental oxygen exposure on myocardial injury in ST-elevation myocardial infarction
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  • Published on:
    Oxygen is toxic during reoxygenation in STEMI patients as well as in other clinical conditions
    • Ola Didrik Saugstad, Professor
    • Other Contributors:
      • Maximo Vento, Professor of Pediatrics Division of Neonatology University & Polytechnic Hospital La Fe, Valencia, Spain

    Nehme and coworkers tested out the effect of air versus oxygen on myocardial injury in ST-elevation myocardial infarction (STEMI).1 When administered in the first 12 hours after STEMI oxygen was associated with a dose-dependent increase in troponin and creatine kinase. In 2015 the same group of investigators published a study in Circulation showing that air instead of oxygen supplementation in STEMI led to improved outco...

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    Conflict of Interest:
    None declared.