Article Text

PDF
Cardiovascular highlights from non-cardiology journals
  1. Patrick J Goleski,
  2. James M McCabe

Statistics from Altmetric.com

Von Willebrand Factor Multimers during Transcatheter Aortic-Valve Replacement

Patients with stenotic or regurgitant aortic valve disease appear to cleave multimers of Von Willebrand factor (HMW-multimer), presumably due to high-shear stresses and non-laminar flow. Van Belle and colleagues hypothesized that transcatheter aortic valve replacement (TAVR) would correct this process, but that significant residual paravalvular leak (PVL) following TAVR would abrogate this corrective effect. Moderate to severe PVL has been associated with increased rates of hospitalization, …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.