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Haemodynamic studies in hypertensive patients treated by oral propranolol
  1. B. N.C. Prichard*,
  2. Elliot Shinebourne,
  3. James Fleming,
  4. John Hamer
  1. Cardiac Department, St. Bartholomew's Hospital, London E.C.1
  2. Medical Unit, University College Hospital Medical School, University Street, London W.C.1

    Abstract

    Haemodynamic studies have been performed in 9 patients whose blood pressures had been satisfactorily controlled with oral propranolol for 7 to 29 months. A postural drop of blood pressure or a fall of blood pressure on exercise did not occur. Pulse rate and cardiac output were below normal at rest and on exercise; peripheral resistance was high. The results are similar to those obtained in a comparable group of hypertensives after acute administration of propranolol. These findings are discussed in relation to the mode of action of propranolol in hypertension.

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    Footnotes

    • * Requests for reprints should be sent to B.N.C.P., Medical Unit, University College Hospital Medical School, University Street, London W.C.1.

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