Article Text


Critical assessment of diagnostic value of endomyocardial biopsy. Assessment of cardiac biopsy.
  1. E H MacKay,
  2. W A Littler,
  3. P Sleight


    Right or left ventricular endomyocardial biopsy with the Konno or the Olympus bioptome was attempted in 73 patients aged 5 months to 61 years, with 82 per cent success. Light and electron microscopy showed non-specific features in over half the biopsies with new or diagnostically useful information in only 10 per cent of cases, usually as a result of electron microscopy. The method is safe but is of strictly limited diagnostic value and is likely to be of most help as a research tool in the biochemical study of cardiomyopathies.

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