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Pathogenesis of heart block in a fatal case of dermatomyositis.
  1. W M Behan,
  2. M Aitchison,
  3. P O Behan

    Abstract

    Approximately 70% of patients with dermatomyositis have evidence of cardiac damage; in one third of cases this affects principally or solely the conduction tissue. In infants similar histological lesions have been associated with a maternal autoantibody, anti-Ro, that crosses the placenta and produces congenital heart block. Anti-Ro antibody was detected in a fatal case of dermatomyositis with lesions of the conduction system.

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