Article Text


Circadian variation in the frequency of onset of chest pain in acute myocardial infarction.
  1. D R Thompson,
  2. T W Sutton,
  3. N I Jowett,
  4. J E Pohl
  1. Coronary Care Unit, Leicester General Hospital.


    The time of onset of chest pain was studied prospectively in 1154 consecutive patients admitted to a coronary care unit with myocardial infarction during a five year period. Statistical analysis confirmed a previous finding in a retrospective study of a bimodal frequency distribution with peaks in the time of onset of chest pain between 2330 and 0030 hours and between 0630 and 0830 hours.

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