Nicorandil abolished repolarisation alternans in a patient with idiopathic long QT syndrome
- Department of Cardiovascular Medicine, Okayama University Medical School, 2-5-1 Shikata, Okayama 700-8558, Japan
- Dr Fujimoto
- Accepted 24 May 1999
Abstract
A 23 year old woman with idiopathic long QT syndrome had repeated syncopal attacks associated with torsades de pointes. T wave alternans (TWA) was recorded and the QT interval was abnormally prolonged during treadmill exercise test. Monophasic action potential (MAP) alternans also appeared after an abrupt shortening of the cycle length in electrophysiological study. After intravenous administration of nicorandil 6 mg, both TWA and MAP alternans disappeared.
