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Management of pregnancy in women with congenital heart disease
  1. LAURENCE ISERIN
  1. Pediatric Cardiology and Adult Cardiology
  2. Necker Hospital
  3. 149, Rue de Sèvres
  4. 75015 Paris
  5. France
  6. laurence.iserin@nck.ap-hop-paris.fr

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The number of women with congenital heart disease reaching childbearing age is increasing, and this group now represents the majority of women with heart disease during pregnancy. This increase raises certain issues which have already been addressed in editorials in this journal,1 ,2 relating to risk factors and the difficulties arising from pregnant women with severe congenital heart disease.

Simple defects

Atrial and ventricular septal defects, and arterial duct, when operated on early in infancy, do not require any special treatment. Asymptomatic left-to-right shunts and moderate pulmonary stenosis are also usually well tolerated. These women should be able to give birth in non-specialist centres. The only concern is prevention of endocarditis in case of residual shunts or valvar regurgitation. Atrial septal defect is the most common congenital heart disease in adults, and in the absence of pulmonary hypertension induces barely any complications.3

Contraindications

Eisenmenger reaction, major or significant aortic dilatation in Marfan syndrome, severe aortic stenosis, deep cyanosis, and heart failure put the patient at high risk of maternal death, even where there is close follow up . Eisenmenger reaction carries up to 50% mortality.1 Recent inquiries in the UK4report maternal death in the range of 2–11/100 000 from 1994-96. The main cardiac causes of death …

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