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Heart 89:1253-1254 doi:10.1136/heart.89.10.1253
  • Scientific letters

The central role of platelet activation in determining the severity of acute coronary syndromes

Table 1

Univariate predictors of diagnosis

Variable Unstable angina (n=64) AMI (n=25) p Value
Data are numbers (%) except for continuous variables where data are mean (SD).
*Glucose and creatinine are log transformed.
ACE, angiotensin converting enzyme; MPC, mean platelet component.
Age (years) 62.5 (12.6) 62.5 (11.9) 0.99
Men 50 (78.1%) 19 (76.0%) 0.83
Diabetes 9 (14.1%) 6 (24.0%) 0.35
Hypertension 31 (48.4%) 7 (28.0%) 0.08
Smoking 18 (28.1%) 12 (48.0%) 0.08
Family history 19 (29.7%) 5 (20.0%) 0.36
Cardiac history 44 (68.8%) 6 (24.0%) 0.0001
Cholesterol (mmol/l) 5.40 (1.40) 5.56 (1.10) 0.64
Glucose* (mmol/l) 1.84 (0.32) 2.24 (0.39) 0.0002
Creatinine* (μmol/l) 4.73 (0.29) 4.68 (0.17) 0.33
Platelets
    Mean platelet volume (fl) 9.1 (1.2) 9.4 (0.9) 0.27
    Mean platelet count (×109/l) 242.3 (66.7) 267.5 (70.6) 0.12
    MPC (g/l) 258.6 (1.38) 246.7 (1.58) 0.001
Admission medication
    Aspirin 44 (68.8%) 4 (16%) <0.0001
    β Blocker 26 (40.6%) 3 (12%) 0.01
    ACE inhibitor 18 (28.6%) 2 (8.0%) 0.05
    Statin 26 (40.6%) 2 (8.0%) 0.002

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