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Heart 90:804-805 doi:10.1136/hrt.2003.022129
  • Scientific letters

Low grade inflammation is notably suppressed by conventional anti-inflammatory treatment: a randomised crossover trial

Table 1

 Median CRP concentrations after placebo and dexamethasone treatment in all subjects and in subjects grouped according to baseline CRP concentration

CRP concentration following placebo (mg/l) CRP concentration following dexamethasone (mg/l) % Change in CRP concentration 95% CI for change in CRP concentration (mg/l) p Value
CI, confidence interval; CRP, C reactive protein
All subjects (n = 18) 0.83 0.16 −80% −0.18 to −1.37 0.001
By basal CRP
    High (n = 6) 2.27 0.45 −80% −1.13 to −4.20 0.036
    Medium (n = 6) 0.74 0.27 −63% −0.170 to −0.77 0.036
    Low (n = 6) 0.12 0.12 0% −0.045 to 0.055 NS

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