Responses
Other responses
Jump to comment:
- Published on: 23 November 2015
- Published on: 23 November 2015
- Published on: 23 November 2015Author's ReplyShow More
Dear Editor,
We agree that the lack of drug specificity indicates that other factors, such as those relating to underlying depression, may explain the associations we have found with myocardial infarction. If amelioration of depression reduces the risk of myocardial infarction, then, yes, antidepressants may reduce the risk of later MI. Our data indicate that people with remaining time on antidepressants for a l...
Conflict of Interest:
None declared. - Published on: 23 November 2015Depressive disorder x antidepressants
Dear Editor,
The lack of difference between the size of the effects associated with tricyclic and selective serotonin reuptake inhibitor antidepressants points to some intrinsic characteristic of the underlying depressive disorder which determined the increased risk of myocardial infarction. Actually, these antidepressants may even have reduced the risk of myocardial infarction later.
Conflict of Interest:
None declared.