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Heart 92:62-67 doi:10.1136/hrt.2004.052787
  • Cardiovascular medicine

Validation of the EuroQol questionnaire in cardiac rehabilitation

  1. B Schweikert1,*,
  2. H Hahmann2,
  3. R Leidl1,*
  1. 1Ludwig-Maximilians University, Munich School of Management, Health Economics and Management, Munich, Germany
  2. 2Schwabenlandklinik, Isny-Neutrauchburg, Germany
  1. Correspondence to:
    Bernd Schweikert
    MSc, Ludwig-Maximilians University, Munich School of Management, Health Economics and Management, Ludwigstraße 28 RG, D-80539 Munich, Germany; schweikert{at}bwl.uni-muenchen.de
  • Accepted 21 March 2005
  • Published Online First 29 March 2005

Abstract

Objective: To analyse the psychometric properties of the EuroQol questionnaire (EQ-5D) applied to patients with acute coronary syndromes (ACS).

Setting: Rehabilitation hospital.

Patients and design: 106 consecutive patients with ACS (51% myocardial infarction, 42% coronary artery bypass grafting, 7% angina) completed the EQ-5D, the 36 item short form health survey (SF-36), and the MacNew questionnaire at admission, at discharge, and three months after inpatient cardiac rehabilitation. Acceptance, validity, reliability, and responsiveness of the EQ-5D were tested.

Results: The EQ-5D was highly accepted. The EQ-5D index showed substantial ceiling effects after rehabilitation. As expected the EQ-5D visual analogue scale (VAS) score (70.3 v 57.1) and EQ-5D index (77.8 v 64.5) were significantly better for patients with myocardial infarction than for patients who underwent surgery (both p ⩽ 0.001). Significant correlations were found between the EQ-5D VAS score, EQ-5D index, and domains of the SF-36 (r  =  0.21 to r  =  0.74). The correlation with the MacNew subscores and with the global score ranged between 0.55 and 0.78. With repeated measurement the EQ-5D showed reasonable reliability in stable patients with intraclass correlation ranging between 0.91 and 0.54. EQ-5D was responsive in patients who indicated improvement in health states between admission and discharge (effect size 0.74–0.82).

Conclusion: The psychometric properties of the EQ-5D were satisfying. It is a reasonably valid, reliable, and responsive instrument for patients with ACS. It may be useful in clinical research and epidemiological studies to generate preference based valuations of health related quality life.

Footnotes

  • * Also the GSF National Research Centre for Environment and Health, Institute of Health Economics and Health Care Management, Neuherberg, Germany

  • Published Online First 29 March 2005

  • Conflicting interest statement: We hereby declare that there are no conflicting interests for any of the authors of this manuscript.