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The authors’ reply:
  1. K Gjesdal,
  2. J Feyzi,
  3. S B Olsson
  1. Arrhythmia Centre, Ullevål University Hospital, Oslo, Norway
  1. Professor K Gjesdal, Arrhythmia Centre, Ullevål University Hospital, Kirkeveien 166, Oslo, 0407 Norway; knut.gjesdal{at}medisin.uio.no

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Testa and coworkers raise a number of questions related to our article1 on suspected increased mortality in patients with atrial fibrillation treated with digitalis. The only method for settling the question would be to perform a randomised controlled clinical trial on digitalis versus placebo in atrial fibrillation, with mortality as the primary outcome. For obvious reasons such a trial will probably not be done. The sample size would need to be large, long-term follow-up would be required, and …

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