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WORKLOAD AT THE HEART RATE OF 100 BEATS/MIN AND MORTALITY IN MIDDLE-AGED MEN WITH KNOWN OR SUSPECTED CORONARY HEART DISEASE

Savonen KP, Lakka TA, Laukkanen JA, Rauramaa TH, Salonen JT, Rauramaa R

Cardiorespiratory performance as well as resting heart rate predict death and cardiac events in persons with known or suspected coronary heart disease (CHD). These findings suggest that workload at the HR of 100 beats/min (WL100), an easily and safely reachable level of exercise for CHD patients, may serve as a useful predictor of death in this patient group. In this prospective study 365 middle-aged men with known or suspected CHD at baseline were followed-up for 11.1 years and it was found that in Cox multivariable models mortality increased by 72% (95% CI 32% to 122%, p<0.001) with 1 SD (34 Watts) decrement in WL100 after adjustment for a range of standard risk factors. The risk of death was 2.4 (95% CI 1.5 …

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