Heart 94:1050-1057 doi:10.1136/hrt.2007.123711
  • Original article
  • Cardiac imaging and non-invasive testing

Assessment of left ventricular mass and volumes by three-dimensional echocardiography in patients with or without wall motion abnormalities: comparison against cine magnetic resonance imaging

Open Access
  1. A-C Pouleur1,
  2. J-B le Polain de Waroux1,
  3. A Pasquet1,
  4. B L Gerber1,
  5. O Gérard2,
  6. P Allain2,
  7. J-L J Vanoverschelde1
  1. 1
    Division of Cardiology, Department of Cardiovascular Diseases, Cliniques Universitaires St Luc, Université Catholique de Louvain, Brussels, Belgium
  2. 2
    Philips Medical Systems Research, Paris, France
  1. Dr Jean-Louis Vanoverschelde, Division of Cardiology, Cliniques Universitaires St Luc, Avenue Hippocrate 10, 2881, B-1200 Brussels, Belgium; vanoverschelde{at}
  • Accepted 11 September 2007
  • Published Online First 1 November 2007


Aim: To evaluate if three-dimensional echocardiography (3-DE) is as accurate and reproducible as cine magnetic resonance imaging (cMR) in estimating left ventricular (LV) parameters in patients with and without wall motion abnormalities (WMA).

Methods: 83 patients (33 with WMA) underwent 3-DE and cMR. 3-DE datasets were analysed using a semi-automatic contour detection algorithm. The accuracy of 3-DE was tested against cMR in the two groups of patients. All measurements were made twice by two different observers.

Results: LV mass by 3-DE was similar to that obtained by cMR (149 (SD 42) g vs 148 (45) g, p = 0.67), with small bias (1 (28) g) and excellent interobserver agreement (−2 (31) g vs 4 (26) g). The two measurements were also highly correlated (r = 0.94), irrespective of WMA. End-diastolic and end-systolic LV volumes and ejection fraction by 3-DE and cMR were highly correlated (r = 0.97, 0.98, 0.94, respectively). Yet, 3-DE underestimated cMR end-diastolic volumes (167 (68) ml vs 187 (70) ml, p<0.001) and end-systolic volumes (88 (56) ml vs 101 (65) ml, p<0.001), but yielded similar ejection fractions (50% (14%) vs 50% (16%), p = 0.23).

Conclusion: 3-DE permits accurate determination of LV mass and volumes irrespective of the presence or absence of WMA. LV parameters obtained by 3-DE are also as reproducible as those obtained by cMR. This suggests that 3-DE can be used to follow up patients with LV hypertrophy and/or remodelling.


  • Competing interests: None.

  • Funding: Work supported by the Fondation Nationale de la Recherche Scientifique of the Belgian Government (FRSM). A-CP is aspirant of the Fondation Nationale de la Recherche Scientifique of the Belgian Government. J-BPW is supported by the Fondation Damman, Louvain-la-Neuve, Belgium.