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Heart 95:1619-1625 doi:10.1136/hrt.2009.173880
  • Original article

Development and validation of a clinical index to predict survival after cardiac resynchronisation therapy

Table 3

Univariate Cox proportional hazard analyses of predictors of mortality

β coefficient (95% CI) HR (95% CI) LR χ2 p Value
Posterolateral scar location 2.82 (1.94 to 3.70 16.8 (6.94 to 40.5) 58.6 <0.0001
CMR-TSI (ms) 0.015 (0.01 to 0.02) 1.01 (1.01 to 1.02) 25.5 <0.0001
Scar burden (%) 0.03 (0.01 to 0.04) 1.03 (1.01 to 1.04) 13.3 0.0001
CMR-LVEF (%) −0.06 (−0.10 to −0.02) 0.94 (0.90 to 0.98) 11.1 0.0032
Sodium (mmol/l) −0.13 (0.04 to −0.04) 0.88 (0.81 to 0.96) 8.2 0.0031
Creatinine (μmol/l) 0.01 (0.00 to 0.02) 1.01 (1.00 to 1.02) 7.92 0.0049
Transmurality (transmural) 0.92 (0.26 to 1.58) 2.51 (1.29 to 4.84) 7.64 0.0057
Male gender 0.95 (−0.08 to 1.99) 2.59 (0.92 to 7.32) 4.15 0.0417
Uric acid (μmol/l) 0.00 (−0.00 to 0.00) 1.00 (1.00 to 1.00) 2.33 0.1265
NYHA class 0.54 (−0.17 to 1.21) 1.73 (0.84 to 3.37) 2.24 0.1343
CABG −0.28 (0.18 to −0.62) 0.75 (0.53 to 1.08) 2.42 0.1196
QRS duration (ms) 0.01 (−0.00 to 0.02) 1.01 (1.00 to 1.02) 1.01 0.2202
Age (years) 0.01 (0.02 to −0.01) 1.01 (0.98 to 1.05) 0.78 0.3765
Atrial fibrillation 0.15 (−0.23 to 0.49) 1.16 (0.80 to 1.63) 0.64 0.4220
Diabetes mellitus −0.17 (−0.55 to 0.28) 0.84 (0.57 to 1.33) 0.61 0.4324
Haemoglobin (g/dl) −0.02 (−0.19 to 0.02) 0.98 (0.83 to 1.02) 0.51 0.4763
  • Variables are listed in order of statistical significance and likelihood ratio χ2 (LR χ2).

  • CABG, coronary artery bypass graft; CI, confidence interval; CMR-TSI, cardiovascular magnetic resonance tissue synchronisation index; CMR-LVEF, cardiovascular magnetic resonance left ventricular ejection fraction; HR, hazard ratio; NYHA, New York Heart Association.

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