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Heart 95:505
  • Featured correspondence
  • Letters

The authors’ response:

  1. A Esposito1,
  2. F De Cobelli1,
  3. G Perseghin2,
  4. A Del Maschio1
  1. 1
    Department of Radiology, San Raffaele Scientific Institute and Vita Salute San Raffaele University, Milan, Italy
  2. 2
    Internal Medicine, Section of Nutrition/Metabolism, San Raffaele Scientific Institute, Milan, Italy
  1. Dr A Esposito, San Raffaele Scientific Institute - Vita Salute San Raffaele University, Via Olgettina 60, Milan 20132, Italy; esposito.antonio{at}hsr.it

    We are grateful to Petersen et al for their letter dealing with relevant concerns about left ventricular (LV) energy metabolism and myocardial fibrosis. Based on their previous experiments in rats with myocardial infarction (MI) induced by coronary ligation1 and on their unpublished data, Petersen et al strongly emphasise the fact that our correlative finding between the extension of late enhancement (LE) and the LV phosphocreatine (PCr)/ATP ratio in humans with hypertrophic cardiomyopathy (HCM)2 may not have a causative relationship. We have a few …

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