Article Text

Periprocedural myocardial injury during elective percutaneous coronary intervention: is it important and how can it be prevented?
  1. F Cuculi,
  2. C C S Lim,
  3. A P Banning
  1. Department of Cardiology, Oxford Radcliffe Hospitals, Oxford, UK
  1. Correspondence to Dr Adrian P Banning, The John Radcliffe, Headley Way, Oxford OX3 9DU, UK; adrian.banning{at}


Periprocedural myocardial injury (PMI) is common after percutaneous coronary intervention (PCI). Periprocedural infarction (myocardial infarction type 4a) occurs after at least 10% of PCI procedures and has an impact on long-term prognosis. Measurement of biomarkers to allow assessment of PMI is an important tool for clinical and research purposes and should be routine after every PCI (troponin I or T and CK-MB). The importance of oral and intravenous antiplatelet agents and other drugs which have been proven to reduce PMI is discussed.

  • PTCA–troponin–statins
  • HMG CoA–clopidogrel–platelet aggregation inhibitors
  • coronary angioplasty
  • coronary stenting
  • microvascular
  • preconditioning
  • anticoagulation

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  • Funding APB is partially funded by the NIHR Biomedical Research Centre Oxford.

  • Competing interests None.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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