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The Authors' reply: We appreciate the letter by Tormen et al1 in response to our paper.2 Atherosclerosis is a multifactorial, slowly progressing vascular disease involving the retention of cholesterol-containing lipoproteins and the generation of proinflammatory molecules that recruit macrophages and ultimately results in thickening of the vascular wall. However, thrombosis is mainly caused by platelet-dependent thrombus formation on pre-existing atherosclerotic plaques.3 Acknowledging that aspirin has anti-inflammatory activity, …
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