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  1. Keith A A Fox1,
  2. Scott McLean2
  1. 1University of Edinburgh & Royal Infirmary of Edinburgh, The Chancellor's Building, 49 Little France Crescent, Edinburgh EH16 4SB, UK
  2. 2Barts and The London NHS Trust, Room 515, John Harrison House, The Royal London Hospital, Whitechapel, London E1 1BB, UK
  1. Correspondence to Professor Keith A A Fox, University of Edinburgh & Royal Infirmary of Edinburgh, The Chancellor's Building, 49 Little France Crescent, Edinburgh EH16 4SB, UK; k.a.a.fox{at}ed.ac.uk

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The Authors' reply: We thank Drs Mamas and Fraser for their interest1 in our recent editorial in Heart on NICE guidance for the investigation of chest pain.2

Please can we point out that our editorial referred specifically to the NICE guidance on chest pain (clinical guidance 95).3 The letter from Mamas and Fraser refers to the separate NICE guidance on unstable angina and non-ST elevation myocardial infarction (MI) (clinical guidance 94).4 Nevertheless, as an author (KAAF) of the GRACE risk score5 and an author (KAAF) of …

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