Article Text
BSCR Autumn Meeting Abstracts, 2009
Myocardial energetics and redox in health and disease
003 Real-time assessment of Krebs cycle metabolism with hyperpolarised [2-13c]pyruvate
Statistics from Altmetric.com
Background and Objectives
The Krebs cycle is fundamental to cardiac energy production, and is often implicated in energetic imbalances characteristic of heart disease. To date, Krebs cycle flux has been measured using 13C-magnetic resonance spectroscopy with isotopomer analysis; however, this approach is limited to the study of steady-state metabolism …