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Response to Peter Joseph
  1. J P Langrish,
  2. N L Mills,
  3. K Donaldson,
  4. D E Newby
  1. University of Edinburgh, Centre for Cardiovascular Science, Edinburgh, UK
  1. Correspondence to Dr Jeremy P Langrish, University of Edinburgh, Centre for Cardiovascular Science, 49 Little France Crescent, Edinburgh EH16 4SB, UK; jeremy.langrish{at}

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The authors' reply: We would like to thank Dr Joseph for his interest and comments on our editorial 1 accompanying the excellent systematic review by Bhaskaran et al.2 As Dr Joseph points out, one of the systematic review's findings was a weak negative association between ozone exposure and the incidence of myocardial infarction.

As Bhaskaran et al indicate, a reduction in ozone concentrations is likely to be a marker of increased combustion-derived fine particulate matter (PM2.5) from vehicle exhaust. Sarnat similarly found that ambient concentrations of O3, NO …

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