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Abstract
131 Ethnic differences in 5 year outcome following percutaneous coronary intervention
  1. I S Toor1,
  2. R Jaumdally1,
  3. G Y H Lip1,
  4. D Pagano2,
  5. W Dimitri3,
  6. T Millane1,
  7. C Varma1
  1. 1City Hospital, Birmingham, UK
  2. 2Queen Elizabeth Hospital, Birmingham, UK
  3. 3University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK

Abstract

Introduction Percutaneous coronary intervention (PCI) is increasingly used for symptomatic relief and for prognostic benefit. However, it is not known if differences in outcomes exist between South Asians and White Europeans offered PCI.

Methods We followed a cohort of 293 South Asians and 865 White Europeans admitted for elective or urgent PCI. Baseline cardiovascular risk factors and angiographic data were obtained. Patients had long-term follow-up (54 (IQR 47–65) months) for all-cause mortality and target lesion revascularisation (TLR).

Results South Asians were younger (62±12 years vs 66±11 years; p<0.0001), with a higher prevalence of diabetes, greater social deprivation (Carstairs Score: 10.2 (IQR 6.5–12.1) vs 3.3 (IQR 0.9–6.5); p<0.0001) and presented more acutely (urgent PCI procedure). During follow-up 119 deaths and 111 TLR (94 repeat PCI and 17 CABG) occurred. Long-term all-cause mortality was similar between South Asians and White Europeans (31(10.6%) vs 107(12.4%); p=0.47). However, South Asian ethnicity was an independent predictor of long-term TLR (54(18.4%) vs 57(6.6%); OR:3.14 (2.01–4.91); p<0.0001) (Abstract 131 Figure 1).

Abstract 131 Figure 1

Long-term target lession revascularisation (TLR) between ethnic groups.

Conclusions South Asian patients with symptomatic coronary artery disease undergoing PCI have a long-term mortality similar to White Europeans. However, South Asians more frequently require readmission for repeat revascularisation due to restenosis.

  • South Asian ethnicity
  • percutaneous coronary intervention
  • long-term outcome

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