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Clinical and research medicine: Interventional cardiology
e0501 1-year clinical outcomes after implantation of sirolimus-eluting stents in patients with coronary artery disease and type 2 diabetes
  1. Han Hongya,
  2. Zhou Yujie,
  3. Ma Hanying,
  4. Liu Yuyang,
  5. Shi Dongmei,
  6. Zhao Yingxin,
  7. Liu Xiaoli,
  8. Gao Fei,
  9. Shen Hua
  1. Beijing Anzhen Hospital

Abstract

Background Drug-eluting stents (DES) have been shown to significantly reduce clinical events and angiographic restenosis in the treatment of coronary artery disease (CAD). We aimed to assess the long-term efficacy and safety of two Sirolimus-Eluting Stents (the biodegradable polymer-coated sirolimus-eluting stents, EXCEL and the polymer-based sirolimus-eluting cobalt-chromium stents, Firebird 2) in the treatment of patients with CAD and Type 2 Diabetes.

Methods A total of 320 consecutive patients with coronary artery disease and type 2 diabetes undergoing percutaneous coronary intervention randomised into two groups (EXCEL group, n=158; Firebird 2 group, n=162). Baseline clinical characteristics, procedural success rate and occurrence of major adverse cardiac events (MACE, a composite of death, myocardial infarction or target lesion revascularisation) during follow-up were recorded and compared between the two groups.

Results During hospitalisation no patient had complications. At 1 year follow-up, both of the EXCEL group and Firebird 2 group had lower occurrence of cardiac events (1.9% in the Excel group and 1.2% in the Firebird group, p>0.05).

Conclusion Implantation of EXCEL stent or Firebird 2 stent for patients with coronary artery disease and type 2 diabetes is safe and can reduce major adverse cardiac events in long-term follow-up.

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