Objective To assess the efficiency of enhanced external counterpulsation (EECP)on silent myocardial ischaemic (SMI)and left ventricular diastolic function (LVDF) in patients with coronary heart disease.
Methods 78 cases of coronary heart disease were randomly into group A (39 cases) and group (39 cases). The group B was treated with normal treatment aspirin, isosorbide mononitrate metoprolol and pavasatatin, the group A was treated with EECP based on the normal treatment for 4 weeks. The changes of myocardial ischaemia and cardiac function were observed by DynamicECG and Doppller echocardiograpy combination with tissue Doppler imaging (TDI) before and after treatment.
Results Frequency and sustained time of ST segment depression, and total loading of myocardial ischaemia were decreased significantly in two groups (p<0.01 respectively) after treatment, but it decreased more significantly (p<0.01) in group A than in routine group B. There was no obvious difference (p>0.05) on the left ventricular systolic function (CO, EF) between the two groups after treatment. LVDF was reduced in patients of two groups before treatment. After treatment indexes of LVDF (E, A, E/A, DC, Ea, Aa, Ea/Aa, E/Ea) were improved (all p<0.01) in the group A, while there were different (p<0.05) in group B before and after treatment. However LVDF in group A was better (p<0.01)than that of group B. No sever adverse effects found in treating with EECP.
Conclusion There has obvious therapeutic efficacy of EECP on SMI and LVDF in patients with coronary heart disease.
- Enhanced external counterpulsation
- Coronary heart disesse
- Silent myocardial ischaemia
- Left ventricular diastolic function
- Dopple echocardiography