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Clinical and research medicine: Coronary heart disease
e0382 Relationship between brain natriuretic peptide levels in patients with acute coronary syndrome after percutaneous coronary intervention and cardiovascular events
  1. Liao Wei,
  2. Zhou Aiqin
  1. The Affiliated Hospital of Gannan Medical College

Abstract

Objective To analyse the relationship between in patients with acute coronary syndrome (ACS) at 48 h after percutaneous coronary intervention (PCI) and the relationship between the variation of brain natriuretic peptide (BNP) and the short and long-term cardiovascular events.

Methods 156 patients with ACS were given conventional preoperative and postoperative medication and standardised PC1. Plasma levels of BNP were measured at 48 h after operations. All patients were divided into two groups according to the level of BNP: A group (BNP>80pg/ml) and B group (BNP<80pg/ml). The incidence of cardiovascular events during hospitalisation and at 6 months after PCI was analysed.

Results Cardiovascular events during hospitalisation in A group included 12 cases, of which 3 died, heart failure occurred in 7 cases; recurrence myocardial infarction and angina in 1 case. 6 months after PCI, there were 4 cases of patients with heart failure and angina occurred in 5 cases. In group B, there were 7 cases of cardiovascular events, 0 deaths, 5 cases of heart failure, angina occurred in 2 cases. Six months later, cardiovascular events occurred in 6 cases, non-cardiac death in 2 cases; heart failure in 3 cases and angina in one. Compared with B group, the incidence of cardiovascular events in A group was significantly higher during hospitalisation (p<0.01), but no different at 6 months after PCI (p>0.05).

Conclusion BNP concentration in patients with ACS at 48 h after PCI can only predict short-term prognosis, but cannot predict the long-term prognosis.

  • acute coronary syndrome (ACS)
  • percutaneous coronary intervention (PCI)
  • brain natriuretic peptide (BNP)

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