Objective To analyse the relationship between in patients with acute coronary syndrome (ACS) at 48 h after percutaneous coronary intervention (PCI) and the relationship between the variation of brain natriuretic peptide (BNP) and the short and long-term cardiovascular events.
Methods 156 patients with ACS were given conventional preoperative and postoperative medication and standardised PC1. Plasma levels of BNP were measured at 48 h after operations. All patients were divided into two groups according to the level of BNP: A group (BNP>80pg/ml) and B group (BNP<80pg/ml). The incidence of cardiovascular events during hospitalisation and at 6 months after PCI was analysed.
Results Cardiovascular events during hospitalisation in A group included 12 cases, of which 3 died, heart failure occurred in 7 cases; recurrence myocardial infarction and angina in 1 case. 6 months after PCI, there were 4 cases of patients with heart failure and angina occurred in 5 cases. In group B, there were 7 cases of cardiovascular events, 0 deaths, 5 cases of heart failure, angina occurred in 2 cases. Six months later, cardiovascular events occurred in 6 cases, non-cardiac death in 2 cases; heart failure in 3 cases and angina in one. Compared with B group, the incidence of cardiovascular events in A group was significantly higher during hospitalisation (p<0.01), but no different at 6 months after PCI (p>0.05).
Conclusion BNP concentration in patients with ACS at 48 h after PCI can only predict short-term prognosis, but cannot predict the long-term prognosis.
- acute coronary syndrome (ACS)
- percutaneous coronary intervention (PCI)
- brain natriuretic peptide (BNP)