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Clinical and research medicine: Coronary heart disease
e0391 Value of testing of carotid artery plaque joint hs-CRP to the degree of coronary stenosis in patients with coronary heart disease
  1. Sheng Yang,
  2. Fu Qiang,
  3. Wei Peng,
  4. Li Zhenyong Yi
  1. Department of Cardiology, Xuzhou Central Hospital

Abstract

Objective To study the predictive value of score of intima-media thickness (IMT), Crouse in carotid artery plaque, and serum levels of high sensitivity C-reactive protein (hs-CRP) in the degree of coronary stenosis of patients with coronary artery disease.

Methods A total of 110 patients suspected coronary heart disease with chest pain were admitted to this study. They were divided into two groups: group of coronary heart disease and group of normal control according to the results of CAG. All patients underwent carotid ultrasonography within a week, and carried out the testing of serum concentrations of hs-CRP in second hospitalised day, to assess the determining and forecasting value of score of IMT and Crouse in carotid artery plaque, combining with serum levels of hs-CRP in the degree of coronary stenosis of patients with coronary artery disease.

Results Serum concentrations of hs-CRP, score of IMT, Crouse of group CHD were significantly higher than those of group non-CHD (p<0.01), and each mentioned indicators in group CHD was positively correlated with the degree of coronary stenosis(r>0.6, p<0.05). Taking Crouse points≥10.7 as a standard, its sensitivity was 78.5%, positive predictive value was 89.9%, specificity was 79.0%, negative predictive value was 58.0%.

Conclusion There was a high consistency between serum concentrations of hs-CRP, score of IMT, Crouse and the degree of coronary stenosis, so we can use serum concentrations of hs-CRP, score of IMT, Crouse as a prediction method to coronary heart disease in patients with carotid artery atherosclerosis.

  • Coronary artery disease
  • carotid artery plaque
  • high sensitivity C-reactive protein

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