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Clinical and research medicine: Coronary heart disease
e0417 Effect of Shengmai injection on cardiac function and inflammatory reaction in patients with acute coronary syndrome
  1. Zhang Yachen,
  2. Chen Man-tian,
  3. Wang Fei,
  4. Rong Yezhi,
  5. Lu Baojing
  1. Division of Cardiology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University

Abstract

Objective To confirm the effect of Shengmai injection in improving cardiac function in patients with acute coronary syndrome (ACS) and to explore its influence on inflammatory reaction in patients.

Methods Ninety ACS patients were randomised into two groups, the control group, treated with conventional therapy and the SMI group, treated with SMI. The patients' cardiac function was noted and the high sensitive C-reactive protein (hs-CRP) in venous blood was measured before treatment and 1 week and 2 weeks after treatment, so as to observe and compare their changes in the two groups.

Results The cardiac output, stroke volume and ejection fraction in the SMI group after 3 weeks of treatment were all higher than those in the control group (p<0.05). The serum content of hsCRP was reduced in both groups, but the reduction in the SMI group was more significant than that in the control group.

Conclusion SMI could improve cardiac function and further inhibit the inflammatory reaction in patients with ACS.

  • Shengmai injection
  • acute coronary syndrome
  • C-reactive protein
  • inflammatory reaction
  • cardiac function

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