Introduction Diabetic patients are prone to a diffuse and rapidly progressive form of atherosclerosis, which increases their likelihood of requiring evascularization. This study was to examine the various therapeutic proportion of the population of the patients with type 2 diabetes mellitus undergone coronary angiography in the era of development in MSCT in the real clinical practice.
Methods One thousand four hundred and six consecutive patients, who underwent CAG at Daxing hospital from February 2007 through to March 2010 were enrolled. Of the 1406 patients, 351 patients were diagnosed as type 2 diabetes mellitus, 1055 patients were diagnosed as non-diabetic mellitus after admission to hospital. By evaluating the coronary angiogram, the patients were not diagnosed to have coronary heart disease (CHD) with less than 50% diameter stenosis of coronary artery; CHD was defined as narrowing of the appropriate lumen of ≥50%; the procedure of percutaneous coronary intervention (PCI) were performed in the patients with more than or equal to 70% stenosis; the coronary aortic bypass graft (CABG) surgery had been proposed in patients with left main coronary artery lesions, left main equivalent, diffuse triple coronary artery lesions, two-vessel disease with significant proximal left anterior descending CAD, however the determinations of the therapeutic choice were combined with clinical data.
Results The baseline characteristics of patients with and without diabetics undergone coronary angiography were as following. The age was significantly older in patients with diabetes than without diabetes (60.22±9.70 vs 57.76±9.94, p<0.0005). More femal patients in the diabetes group than non-diabetes group (45.30% vs 35.55%, p<0.0005). The morbidity rate of UAP (64.96% and 49.86%, p<0.0005), and Hypertension (80.06% and 69.57%, p<0.0005) were significantly higher in patients with diabetes than without diabetes. By evaluating the coronary angiogram, more patients were diagnosed to CHD in the diabetes group than in the non-diabetic group (92.59% vs 79.43%, p<0.0005); the proportion of the population of the patients with CHD not indicated for PCI was almost identical in the two groups (23.30% vs 25.97%, p=0.33); the proportion of the patients with CHD performed the procedure of stent implantation (including the patients receiving follow-up coronary angiography after stenting) were not differ significantly between the two groups (35.61% vs 32.61%, p=0.30); more patients with CHD were proposed to perform the CABG in the diabetes group than in the non-diabetic group (31.91% vs 17.35%, p<0.0005).
Conclusion The morbidity rate of coronary heart disease among patients with type 2 diabetes is greater than non-diabetes, patients with type 2 diabetes have a significantly higher rate of coronary artery bypass grafting which had been proposed.