Severe retrograde dissection extending into the sinus of Valsalva is a rare complication during percutaneous coronary intervention (PCI), but life threatening. The danger of this event depends on two aspects: first, the potential occlusion of the related coronary artery and second, the possibility of the dissection extending to the ascending aorta and further. There is some literature about this complication, but this particular complication has not been previously reported in China. We think that the rarity and unknown significance of this complication have probably led to a general underreporting in our country. We present a case of coronary artery dissection during a PCI in which progressively extended retrogradely into the sinus of valsalva, and was successfully treated with stenting without an operation.