Objective To evaluated the safety and efficacy of Endeavor Stent in patients with coronary heart disease (CHD) and diabetes performed percutaneous coronary intervention (PCI) via trans-radial artery approach for de novo lesions by comparing with Cypher stent.
Methods A total of 96 in-hospital patients with CHD and diabetes who performed PCI via trans-radial approach for de novo lesions were randomised into two groups: Endeavour group (EG, n=52), Cypher group (CG, n=44). The minimal luminal diameter, diameter stenosis, incidence of restenosis and major adverse cardiac events of two groups instant and 6 months’ follow-up after PCI were compared.
Results There are no significant differences between the two groups in baseline characteristics. There was no significant differences between the two groups in target-vessel distribution and ACC/AHA classification. 62.95% lesions treated were Type B2/C and 57.26% lesions were in left anterior descending artery. The average length of lesion, diameter of reference vessel, multivessel lesions, release pressure were no significant difference between the two group. Success rate of PCI was 100% in both of the two groups. All of the 96 patients were finished clinical follow up, among them, CAG were reperformed in 52 patients, 28 cases in EG and 24 cases in CG. The average follow-up period was no obvous difference between the two groups. There was no patient died in hospital. Each group had 1case happened AMI (for subacute thrombosis 3 days post-PCI in CG, and infarction of another vessel in EG. Three patients in EG, while four in CG occurred angina, two of which in each group were suffered from intra-stent restenosis. There was no significant difference between the two groups in minimal luminal diameter and diameter stenosis (p>0.05) before, instantly after and 6 months after PCI, as well in early gain and late loss, restenosis rate and major adverse cardiac events (p all>0.05).
Conclusion Endeavour Stent was as safe and efficient as Cypher stent in patients with CHD and diabetes.