Objective To investigate the safety and efficacy of sirolimus eluting stent implantation in small diameter renal artery.
Methods 32 sirolimus eluting coronary stent (3.0∼4.0 mm) were implanted in 26 patients with hypertension. Patients were followed for a median of 12 months with measurements of blood pressure, serum urea nitrogen and serum creatinine, duplex sonography and intra-arterial angiography.
Results Initial technical success was achieved in all patients. Renal artery dissection occurred in one patients after stent implantation. During follow up, amelioration of blood pressure was achieved in six patients (23.1%), amelioration of renal dysfunction was achieved in three patients (11.5%), deterioration of renal dysfunction occurred in three patients (11.5%). In-stent restenosis occurred in two patients, one found by angiography at the 10th month after stent implantation, another by duplex sonography at the 16th month after stent implantation.
Conclusion Implantation of sirolimus eluting coronary stents in small diameter renal artery is technically feasible with efficacy and safety. Although there was no in-stent restenosis during the first 6 months after stent implantation, in-stent restenosis could occur later. Patients with sirolimus eluting coronary stent implantation in small diameter renal artery should be followed for more than one year.