Background The benefits of lowering systolic blood pressure (SBP) below140 mm Hg in elderly patients with type 2 diabetes and hypertension are unclear.
Methods Elderly (age ≥65 years) patients with type 2 diabetes and hypertension underwent 12-lead ECG. The R-wave voltage in lead aVL (RaVL ≥0.57 mV) was used to assess CVD risk. GFR was estimated by Cockcroft-Gault formula. 235 patients were tight SBP controlled (130–139 mm Hg), and 472 patients were less tight SBP controlled (140–159 mm Hg).
Results The height of RaVL and risk of the height of RaVL ≥0.57 mV was no significance difference between the two groups, but some decline in eGFR was found in the less tight control group (adjusted mean 55.61 vs 59.65, p=0.06) although the decrease was not statistically significant.
Conclusions In elderly patients with type 2 diabetes and hypertension, to achieve the target SBP of below 140 mm Hg seems reasonable.