Objective The subendocardial viability ratio (SEVR) measures myocardial perfusion related to cardiac workload. The chief aim of this work was to investigate the relationship between SEVR and cardiovascular risk factors.
Methods This study examined 1025 subjects, who underwent a health check-up with thorough medical examination between February and May 2008. Subjects were divided into six groups by age, and three groups by blood pressure. Plasma total cholesterol (TCH), high-density and low-density lipoprotein cholesterol (HDLC, LDLC), triglycerides (TG), fasting plasma glucose, and serum creatinine levels were measured enzymatically. Central aortic waveforms and pressures were calculated using a SphygmoCor pulse wave analysis (PWA) system.
Results The Buckberg SEVR gradually decreased as age increased, while the slopes of the aortic augmentation and aortic augmentation indices increased. The SEVR was 150.11±24.70% in a pre-hypertension group and 139.87±24.98% in a hypertension group, which was lower than the normal blood pressure group. Smoking, alcohol ingestion and deficiency in physical activity decreased SEVR. The SEVR was significantly associated with age, brachial systolic and diastolic blood pressure, brachial pulse pressure, aortic systolic blood pressure and pulse pressure, heart rate, aortic augmentation, aortic augmentation index at heart rate 75, total cholesterol, smoking and alcohol consumption.
Conclusion We found that SEVR decreased as age increased. SEVR was decreased in pre-hypertension compared to hypertension groups. Smoking, alcohol ingestion and deficiency in physical activity may be factors that affect SEVR.