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Epidemiology and preventive medicine: Obesity
e0312 Evaluation on the diagnostic value of body mass index in predicting obstructive sleep apneahypopnea syndrome in Chinese adults
  1. Zeng Jin,
  2. GU Yalan,
  3. MA Furong
  1. The Third Hospital of Peking University

Abstract

Objective To evaluate diagnostic value of body mass index (BMI) in screening and diagnosing obstructive sleep apnoea-hypopnoea syndrome and to determine the reference standard of body mass index (BMI) in both male and female population by receiver operating characteristic (ROC) curve.

Method A total of 1348 subjects (1063 male and 285 female) who experienced polysomnography (PSG) during 2004–2010 in The Third Hospital of Peking University ENT department were included. The correlativity between apnoea-hypopnoea index (AHI) and BMI was conducted by pearson correlation test. The diagnostic value and reference standard in both male and female were analysed by ROC curve.

Result 1) A positive relationship between AHI and BMI was detected, both in male and female subjects, with pearson coefficients 0.423 and 0.419 (p<0.001). 2) Results of ROC analysis show a favourable value of BMI in diagnosing OSHAS, especially in male subjects. In male population, area under curve (AUC) was 0.759 (95% CI 0.724 to 0.795) with a best cutoff value 25.3 kg/m2. The sensitivity and specificity in man were 74% and 61%, respectively; in women, area under curve (AUC) was 0.691 (95% CI 0.632 to 0.751) with a best cutoff value 24.7 kg/m2. The sensitivity and specificity were 68% and 61%. The screening cutoff values were 22.4 kg/m2 and 20.7 kg/m2 in male and female, with a sensitivity of 95%. The diagnostic cutoff values were 30.0 kg/m2 and 36.0 kg/m2, with a specificity of 95%.

Conclusion BMI seemed a better diagnostic value of OSAHS in diagnosing than screening, especially in male population. Sexual-separated cutoff values should be use in clinical practice to enhance diagnostic accuracy.

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