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Controversies with On-TIME 2
  1. Gen-Min Lin1,
  2. Yi-Hwei Li2,
  3. Kai-Min Chu3,
  4. Chih-Lu Han4
  1. 1Hualien Armed Forces General Hospital, Hualien, Taiwan
  2. 2Tzu-Chi University, Hualien, Taiwan
  3. 3Tri-Service General Hospital, Taipei, Taiwan
  4. 4Taipei Veterans General Hospital, Taipei, Taiwan
  1. Correspondence to Gen-Min Lin, Hualien-Armed Forces General Hospital, Hualien, Taiwan, Province of China; farmer507{at}

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To the Editor We appreciate the work by Hermanides et al, which reported that routine prehospital treatment with high-dose tirofiban (HDT) significantly reduces the use of blinded bail-out study medication (20% vs 29%). The need for bail-out therapy was associated with a less favourable outcome (major adverse cardiac events (MACE) at 30 days 12.2% …

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